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Elsa Shapiro Selected Research

heparan sulfate sulfatase

12/2021Long-term safety and clinical outcomes of intrathecal heparan-N-sulfatase in patients with Sanfilippo syndrome type A.
9/2021A multicenter open-label extension study of intrathecal heparan-N-sulfatase in patients with Sanfilippo syndrome type A.
1/2019Intrathecal heparan-N-sulfatase in patients with Sanfilippo syndrome type A: A phase IIb randomized trial.

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Elsa Shapiro Research Topics

Disease

6Mucopolysaccharidosis I (Hurler Syndrome)
09/2019 - 07/2007
5Mucopolysaccharidoses
12/2021 - 01/2014
4Mucopolysaccharidosis III (Sanfilippo Syndrome)
12/2021 - 01/2018
2Mental Disorders (Mental Disorder)
09/2019 - 02/2014
2Cognitive Dysfunction
03/2017 - 09/2012
2Pain (Aches)
04/2016 - 01/2014
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2018
1Disease Progression
01/2018
1Inflammation (Inflammations)
04/2016
1Chronic Pain
04/2016
1Autistic Disorder (Autism)
05/2014
1Brain Diseases (Brain Disorder)
02/2014
1Bone Resorption
01/2014
1Neoplasms (Cancer)
09/2012

Drug/Important Bio-Agent (IBA)

3heparan sulfate sulfataseIBA
12/2021 - 01/2019
3Iduronidase (alpha-L-Iduronidase)IBA
09/2019 - 07/2007
3EnzymesIBA
09/2019 - 05/2014
2Heparitin Sulfate (Heparan Sulfate)IBA
09/2021 - 01/2019
2Biomarkers (Surrogate Marker)IBA
01/2018 - 01/2014
1SolutionsIBA
03/2017
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2016
1Nonsense Codon (Nonsense Mutation)IBA
02/2014
1pyridinolineIBA
01/2014
1Alkaline PhosphataseIBA
01/2014
1OsteocalcinIBA
01/2014
1deoxypyridinolineIBA
01/2014

Therapy/Procedure

6Therapeutics
12/2021 - 04/2016
4Enzyme Replacement Therapy
12/2021 - 07/2007
1Drug Therapy (Chemotherapy)
09/2012
1Cell Transplantation
09/2012